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Phenotypes Associated with This Genotype
Genotype
MGI:4454673
Allelic
Composition		 Kdrtm1Jrt/Kdr+
Tmem204tm1.1Ali/Tmem204tm1.1Ali
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdrtm1Jrt mutation (1 available); any Kdr mutation (73 available)
Tmem204tm1.1Ali mutation (0 available); any Tmem204 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal lymphatic vessel smooth muscle morphology ( J:159519 )
• abnormal smooth muscle cell coating
enlarged lymphatic vessel ( J:159519 )
• enlarged lymphatic vessels are even more dilated than in Tmem204tm1.1Ali single knock-outs

muscle
abnormal lymphatic vessel smooth muscle morphology ( J:159519 )
• abnormal smooth muscle cell coating

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory