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Phenotypes Associated with This Genotype
Genotype
MGI:4458087
Allelic
Composition		 Trpv1tm1Jbd/Trpv1tm1Jbd
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trpv1tm1Jbd mutation (0 available); any Trpv1 mutation (61 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal sensory neuron physiology ( J:161343 )
• vagal neurons fail to respond to capsaicin unlike similarly treated wild-type mice
• vagal neurons lack response to 100 uM 4-oxononenal (4ONE) unlike similarly treated wild-type cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory