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Phenotypes Associated with This Genotype
Genotype
MGI:4459402
Allelic
Composition
Tpbgtm1Plst/Tpbgtm1Plst
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tpbgtm1Plst mutation (0 available); any Tpbg mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• embryonic stem cells treated with DECMA-1 antibodies fail to exhibit a mesenchyme phenotype unlike similarly treated wild-type cells
• in the absence of LIF, embryonic stem cells do not exhibit as much of an increase in migration as similarly treated wild-type cells and lack a motile phenotype


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory