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Phenotypes Associated with This Genotype
Genotype
MGI:4818353
Allelic
Composition		 Fgf22tm1Dgen/Fgf22tm1Dgen
Genetic
Background		 B6.Cg-Fgf22tm1Dgen
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf22tm1Dgen mutation (0 available); any Fgf22 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
decreased susceptibility to pharmacologically induced seizures ( J:161954 )
• pentylenetetrazol-treated mice fail to exhibit seizures at doses that elicit seizures in wild-type mice

nervous system
decreased susceptibility to pharmacologically induced seizures ( J:161954 )
• pentylenetetrazol-treated mice fail to exhibit seizures at doses that elicit seizures in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory