About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4819101
Allelic
Composition		 Nogtm1Amc/Nogtm1Amc
Smad3tm1Xfw/Smad3tm1Xfw
Genetic
Background		 involves: 129/Sv * 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nogtm1Amc mutation (3 available); any Nog mutation (18 available)
Smad3tm1Xfw mutation (0 available); any Smad3 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
holoprosencephaly ( J:161524 )
• in 60% of mice

embryo
abnormal embryonic tissue morphology ( J:161524 )
• 60% (18 of 30) show defects in anterior midline tissues

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory