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Phenotypes Associated with This Genotype
Genotype
MGI:4819847
Allelic
Composition		 Nf2tm2Gth/Nf2tm2Gth
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nf2tm2Gth mutation (3 available); any Nf2 mutation (65 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal lens morphology ( J:162628 )
• ectopic cells accumulate in the equator and posterior of the lens unlike in wild-type mice
abnormal lens epithelium morphology ( J:162628 )
• in the anterior region

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory