Phenotypes Associated with This Genotype

Genotype
MGI:4822376

• Allelic Composition: Bmp5^se-5RD300H/Bmp5^se-5RD300H
• Genetic Background: involves: 101/Rl * C3H/Rl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:12013 , J:100221 )

embryonic lethality between somite formation and embryo turning, complete penetrance ( J:5268 )

• homozygous mutant mice die prior to day 8

embryo

decreased embryo size ( J:5268 )

• reduced size relative to normal

absent mesoderm ( J:5268 )

• nearly total absence of mesoderm

increased trophoblast giant cell number ( J:5268 )

abnormal extraembryonic ectoderm morphology ( J:5268 )

• extensive proliferation of extraembryonic ectoderm

growth/size/body

decreased embryo size ( J:5268 )

• reduced size relative to normal