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Phenotypes Associated with This Genotype
Genotype
MGI:4830344
Allelic
Composition
Recktm1Ito/Recktm1Ito
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Recktm1Ito mutation (1 available); any Reck mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• at E10.5, the series of periodically spaced contact zones in the pernineural vascular basement membrane compared to in wild-type mice
• at E10.5
• at E10.5, mice exhibit abdominal hemorrhage unlike wild-type mice

embryo
• yolk sacs exhibit irregularly shaped sprouts or branches instead of the numerous small holes in the arterial domain observed in wild-type mice
• in the lateral regions, arteries are winding and variable in thickness compared to in wild-type yolk sac


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory