Phenotypes Associated with This Genotype

Genotype
MGI:4835971

• Allelic Composition: Tg(Eno2-Hgf)1Tnak/0; Tg(SOD1*G93A)^dl1Gur/0
• Genetic Background: involves: C57BL/6 * C57BL/6J * SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

microgliosis ( J:128738 )

• decreased numbers of microglia compared with Tg(SOD1*G93A)^dl1Gur mice in facial and hypoglossal nuclei at 8 months of age

astrocytosis ( J:128738 )

• decreased numbers of reactive astrocytes compared with Tg(SOD1*G93A)^dl1Gur mice in facial and hypoglossal nuclei at 8 months of age

abnormal motor neuron morphology ( J:128738 )

• less atrophic facial and hypoglossal motoneurons at 8 months of age

• the mean numbers of facial and hypoglossal motoneurons are larger than that of the Tg(SOD1*G93A)^dl1Gur mice, and are almost the same as that of wild type mice

immune system

microgliosis ( J:128738 )

• decreased numbers of microglia compared with Tg(SOD1*G93A)^dl1Gur mice in facial and hypoglossal nuclei at 8 months of age

hematopoietic system

microgliosis ( J:128738 )

• decreased numbers of microglia compared with Tg(SOD1*G93A)^dl1Gur mice in facial and hypoglossal nuclei at 8 months of age