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Phenotypes Associated with This Genotype
Genotype
MGI:4836837
Allelic
Composition		 Tfpitm1.1Rdsi/Tfpitm1.1Rdsi
Tg(Tek-cre)12Flv/0
Genetic
Background		 involves: 129S4/SvJaeSor * 129S6/SvEvTac * BALB/cJ * C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tfpitm1.1Rdsi mutation (1 available); any Tfpi mutation (47 available)
Tg(Tek-cre)12Flv mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal circulating protein level ( J:164530 )
• decreased tissue factor pathway inhibitor protein level and activity
increased susceptibility to induced thrombosis ( J:164530 )
• in a FeCl3 arterial injury model, carotid arteries become occluded faster than in control mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory