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Phenotypes Associated with This Genotype
Genotype
MGI:4838307
Allelic
Composition		 Cfptm1Song/Cfptm1Song
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cfptm1Song mutation (0 available); any Cfp mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
impaired complement alternative pathway ( J:165497 )
• LPS-induced alternative pathway (AP) complement activation is impaired unlike in wild-type mice
• however, zymosan-induced AP complement activation is normal

skeleton

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory