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Phenotypes Associated with This Genotype
Genotype
MGI:4840057
Allelic
Composition		 Ctshtm1Thre/Ctshtm1Thre
Genetic
Background		 B6N.129P2-Ctshtm1Thre
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctshtm1Thre mutation (0 available); any Ctsh mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
abnormal respiratory system physiology ( J:178096 )
• bronchoalveolar fluid exhibits impaired surface tension compared with wild-type mice
decreased surfactant secretion ( J:178096 )
• mice exhibit reduced surfactant B protein in the bronchoalveolar lavage compared with wild-type mice

reproductive system
reproductive system phenotype ( J:178096 )
N
• mice exhibit normal reproduction

growth/size/body
growth/size/body region phenotype ( J:178096 )
N
• normal growth

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory