Phenotypes Associated with This Genotype

Genotype
MGI:4840224

• Allelic Composition: Myf5^tm3(cre)Sor/Myf5⁺; Stat5b^tm1Mam/Stat5b^tm1Mam; Tg(Alb1-cre)1Dlr/0
• Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:119237 )

• modest increase in body fat at 8 weeks of age

growth/size/body

decreased lean body mass ( J:119237 )

• reduced lean mass at 8 weeks of age

• reduction in fraction of lean mass at 8 weeks of age

decreased body weight ( J:119237 )

• 12% and 20% smaller for female and male mice respectively, at 8 wk of age

decreased body length ( J:119237 )

• reduced body length at 8 weeks of age

homeostasis/metabolism

decreased circulating insulin-like growth factor I level ( J:119237 )

• 60% decrease in circulating IGF-I level at 8 weeks of age