liver/biliary system
• about a 40% increase in liver mass following adenoviral cre retro-orbital injection
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• increase in hepatocyte size following adenoviral cre retro-orbital injection
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• decrease in liver protein content following adenoviral cre retro-orbital injection
• in cre injected mice, the liver is largely refractory to fast induced shrinkage
• cre injected mice are unable to generate ketones when given sodium octanoate
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homeostasis/metabolism
• markedly lower serum ketones in young fasted cre injected mice but not in aged fasted cre injected mice
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• in fasted cre injected mice
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behavior/neurological
• in fasted cre injected mice
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growth/size/body
• about a 40% increase in liver mass following adenoviral cre retro-orbital injection
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