Phenotypes for Ift122 Shh MGI:4888266 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ift122^sopb/Ift122^sopb Shh^tm1Chg/Shh^tm1Chg
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift122^sopb mutation (0 available); any Ift122 mutation (52 available)
Shh^tm1Chg mutation (2 available); any Shh mutation (48 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal neural tube morphology ( J:168317 )

• at E10.5 the neural tube is ventralized similar to the phenotype in mice homozygous for Ift122^sopb alone

open neural tube ( J:168317 )

nervous system

abnormal neural tube morphology ( J:168317 )

• at E10.5 the neural tube is ventralized similar to the phenotype in mice homozygous for Ift122^sopb alone

open neural tube ( J:168317 )

exencephaly ( J:168317 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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