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Phenotypes Associated with This Genotype
Genotype
MGI:4941323
Allelic
Composition		 Rag2tm2.1Desi/Rag2tm2.1Desi
Trp53tm1Tyj/Trp53tm1Tyj
Genetic
Background		 involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rag2tm2.1Desi mutation (0 available); any Rag2 mutation (117 available)
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (232 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased T cell derived lymphoma incidence ( J:168974 )
• in half of mice by 20 weeks, similar to in Trp53tm1Tyj homozygotes

endocrine/exocrine glands
increased T cell derived lymphoma incidence ( J:168974 )
• in half of mice by 20 weeks, similar to in Trp53tm1Tyj homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory