Phenotypes Associated with This Genotype

Genotype
MGI:4943914

• Allelic Composition: Grin2b^tm1Mim/Grin2b⁺
• Genetic Background: B6.Cg-Grin2b^tm1Mim

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased startle reflex ( J:89405 )

• enhanced startle response when presented with 60 startle stimuli of 120-dB bursts of sound for 50 ms over the 30-min test

• enhanced startle response at sound levels of 90 - 120 dB

• however, no differences in ABR thresholds are detected compared to wild-type mice

nervous system

increased prepulse inhibition ( J:89405 )

• slightly increased