Phenotypes Associated with This Genotype

Genotype
MGI:4946401

• Allelic Composition: Selenon^tm1.2Mred/Selenon^tm1.2Mred
• Genetic Background: involves: 129S2/SvPas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

skeletal muscle atrophy ( J:168699 )

• after successive regeneration cycles

decreased satellite cell number ( J:168699 )

• in uninjured and injured mice

abnormal muscle physiology ( J:168699 )

• proliferation of muscle precursors is increased compared to in wild-type mice

abnormal muscle regeneration ( J:168699 )

• after successive injury, muscle regeneration is impaired and regenerating muscle tissue is replaced by fibrosis, adipocytes, and necrotic fibers compared with wild-type mice