Phenotypes for Ranbp1 MGI:4946609 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ranbp1^tm1Yyo/Ranbp1^tm1Yyo
Genetic Background	involves: 129S2/SvPas * C57BL/6

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ranbp1^tm1Yyo mutation (0 available); any Ranbp1 mutation (68 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:170335 )

N	• female mice are fertile

abnormal male germ cell apoptosis ( J:170335 )

abnormal spermatogenesis ( J:170335 )

• spermatogenesis is impaired at sperm elongation unlike in wild-type mice

azoospermia ( J:170335 )

male infertility ( J:170335 )

growth/size/body

decreased body weight ( J:170335 )

• at 12 weeks

postnatal growth retardation ( J:170335 )

cellular

azoospermia ( J:170335 )

abnormal male germ cell apoptosis ( J:170335 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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