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Phenotypes Associated with This Genotype
Genotype
MGI:5051645
Allelic
Composition
Nf2tm2Gth/Nf2tm2Gth
Genetic
Background
involves: 129P2/OlaHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nf2tm2Gth mutation (3 available); any Nf2 mutation (65 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• later postnatal inactivation of Nf2 in arachnoidal cells by injection of adenoviral cre into the cerebro-spinal fluid of 10 day-old pups or adult mice does not result in meningioma formation, in contrast to embryonic Nf2 deletion or previous data for inactivation in 1-2 day-old mice

nervous system
• later postnatal inactivation of Nf2 in arachnoidal cells by injection of adenoviral cre into the cerebro-spinal fluid of 10 day-old pups or adult mice does not result in meningioma formation, in contrast to embryonic Nf2 deletion or previous data for inactivation in 1-2 day-old mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory