Phenotypes Associated with This Genotype

Genotype
MGI:5056120

• Allelic Composition: Tg(Sox10-cre)1Wdr/0; Twsg1^tm1Aptr/Twsg1^tm1Aptr
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal frontonasal prominence morphology ( J:173627 )

• mice exhibit midline fusion of the frontonasal prominences compared with wild-type mice

fused first pharyngeal arch ( J:173627 )

small first pharyngeal arch ( J:173627 )

embryo

fused first pharyngeal arch ( J:173627 )

small first pharyngeal arch ( J:173627 )

nervous system

abnormal telencephalon development ( J:173627 )

• mice exhibit non-septation of the telencephalic vesicles compared with wild-type mice