Phenotypes Associated with This Genotype

Genotype
MGI:5290082

• Allelic Composition: Ift172^avc1/Ift172^wim
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal motile primary cilium morphology ( J:175371 )

• severely decreased mean ventral node cilia length at E7.5

cellular

abnormal cilium morphology ( J:175371 )

• decrease in the percentage of MEFs with cilia compared to wild-type MEFs

• severely decreased cilia length on MEFs with a large population of truncated cilia and a much smaller population of full length cilia

abnormal motile primary cilium morphology ( J:175371 )

• severely decreased mean ventral node cilia length at E7.5

cardiovascular system

abnormal cardiovascular system morphology ( J:175371 )

• cardiac abnormalities

craniofacial

abnormal craniofacial morphology ( J:175371 )

• craniofacial abnormalities

limbs/digits/tail

abnormal limb morphology ( J:175371 )

• limb abnormalities