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Phenotypes Associated with This Genotype
Genotype
MGI:5293365
Allelic
Composition		 Phox2btm4Jbr/Phox2b+
Tg(Pgk1-cre)1Lni/0
Genetic
Background		 involves: 129S2/SvPas * BALB/c * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Phox2btm4Jbr mutation (1 available); any Phox2b mutation (25 available)
Tg(Pgk1-cre)1Lni mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

nervous system
abnormal retrotrapezoid nucleus morphology ( J:176573 )
• massive depletion of retrotrapezoid nucleus neurons

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory
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