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Phenotypes Associated with This Genotype
Genotype
MGI:5295152
Allelic
Composition		 Flt4Chy/Flt4Chy
Genetic
Background		 involves: C3H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flt4Chy mutation (2 available); any Flt4 mutation (77 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal lymphangiogenesis ( J:177405 )
• mice exhibit disrupted lymph sac formation and lymphatic growth
absent lymphatic vessels ( J:177405 )
• at E13.5 and E15.5

homeostasis/metabolism
edema ( J:177405 )
• at E15.5

cardiovascular system
cardiovascular system phenotype ( J:177405 )
N
• blood vessel formation is normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory