Phenotypes for Lep Stxbp5l MGI:5297580 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Lep^ob/Lep^ob Stxbp5l^T2dm1/Stxbp5l^T2dm1
Genetic Background	B6.Cg-Lep^ob Chr 16^BTNTTF

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lep^ob mutation (5 available); any Lep mutation (23 available)
Stxbp5l^T2dm1 mutation (0 available); any Stxbp5l mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased circulating glucose level ( J:178002 )

• mice exhibit increased fasting serum glucose compared with Lep^ob homozygotes

decreased circulating insulin level ( J:178002 )

• mice exhibit decreased fasting serum insulin compared with Lep^ob homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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