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Phenotypes Associated with This Genotype
Genotype
MGI:5299161
Allelic
Composition		 Mecp2tm1Jae/Y
Tg(Camk2a-Setdb1)1Akba/0
Tg(Nes-cre)1Atp/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2tm1Jae mutation (2 available); any Mecp2 mutation (41 available)
Tg(Camk2a-Setdb1)1Akba mutation (0 available)
Tg(Nes-cre)1Atp mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:178512 )
• mice die between 8 and 40 weeks of age

behavior/neurological
decreased locomotor activity ( J:178512 )
• worse than in Mecp2tm1Jae/Y mice

growth/size/body
decreased body weight ( J:178512 )

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory