Phenotypes Associated with This Genotype

Genotype
MGI:5299345

• Allelic Composition: Creb1^tm1.1Berd/Creb1^tm1.1Berd
• Genetic Background: B6NHsd.129S4-Creb1^tm1.1Berd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

increased myoblast proliferation ( J:177923 )

• myotube density is slightly increased due to increased myoblast proliferation

• however, myoblasts differentiate normally into myotubes

muscle

muscle phenotype ( J:177923 )

N • mice exhibit normal muscle structure

increased myoblast proliferation ( J:177923 )

• myotube density is slightly increased due to increased myoblast proliferation

• however, myoblasts differentiate normally into myotubes

abnormal myotube morphology ( J:177923 )

• myotube density is slightly increased due to increased myoblast proliferation

enhanced skeletal muscle regeneration ( J:177923 )

• regenerating muscle exhibits increased cell proliferation compared to in wild-type mice