Phenotypes for Nr3c1 Tg(Sim1-cre)1Lowl MGI:5306344 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Nr3c1^tm1.1Mvc/Nr3c1⁺ Tg(Sim1-cre)1Lowl/0
Genetic Background	involves: 129 * C57BL/6 * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr3c1^tm1.1Mvc mutation (0 available); any Nr3c1 mutation (35 available)
Tg(Sim1-cre)1Lowl mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body weight ( J:179918 )

• during adulthood

homeostasis/metabolism

increased circulating corticosterone level ( J:179918 )

increased circulating adrenocorticotropin level ( J:179918 )

nervous system

abnormal hypothalamus physiology ( J:179918 )

• elevated immunoreactivity for corticotropin-releasing hormone in the paraventricular nucleus

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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