Phenotypes Associated with This Genotype

Genotype
MGI:5306650

• Allelic Composition: Cbx8^tm1.1Hko/Cbx8^tm1.1Hko
• Genetic Background: involves: 129 * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:178955 )

N • mice are viable

cellular

abnormal cell physiology ( J:178955 )

• MigR1-MLL-AF9-transformed bone marrow cells exhibit impaired initiation and maintenance of leukemic transformation

hematopoietic system

hematopoietic system phenotype ( J:178955 )

N • mice exhibit normal hematopoiesis, long-term hematopoietic stem cell maintenance, and stem and progenitor cell function