Phenotypes for Grin2b Neurod6 MGI:5307061 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Grin2b^tm1.1Jlbr/Grin2b^tm1.1Jlbr Neurod6^tm1(cre)Kan/Neurod6⁺
Genetic Background	involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grin2b^tm1.1Jlbr mutation (0 available); any Grin2b mutation (100 available)
Neurod6^tm1(cre)Kan mutation (0 available); any Neurod6 mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal suckling behavior ( J:178913 )

• at P0 a decrease in the number of rhythmic mouth suckling movements in response to stimulation with a feeding needle is seen

• lack of milk in the stomach at P0

increased locomotor activity ( J:178913 )

• increased spontaneous locomotion at P15-P21

social withdrawal ( J:178913 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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