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Phenotypes Associated with This Genotype
Genotype
MGI:5308944
Allelic
Composition
Sgcetm2.1Ygl/Sgce+
Tg(Pcp2-cre)2Mpin/0
Genetic
Background
involves: 129S1/Sv * 129S2/SvPas * 129S4/SvJaeSor * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sgcetm2.1Ygl mutation (0 available); any Sgce mutation (44 available)
Tg(Pcp2-cre)2Mpin mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• when the allele is inherited paternally, mice exhibit normal posture, righting response, motor coordination and balance
• when the allele is inherited paternally, mice do not exhibit significant myoclonus
• when the allele is inherited paternally, mice exhibit impaired motor learning on a beam-walking test compared with control mice
• activity, movement number and movement time when the allele is inherited paternally

nervous system
N
• when the allele is inherited paternally, Purkinje cells exhibit normal nuclear envelops


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory