Phenotypes Associated with This Genotype

Genotype
MGI:5312919

• Allelic Composition: Tg(Hnf1a-RB1*)XMiu/?
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

liver/biliary system

abnormal hepatocyte morphology ( J:180294 )

• hepatocyte dysplasia is detected at 8 months of age

• at 8 months of age some hepatocytes and nuclei are enlarged

increased liver adenoma incidence ( J:180294 )

• about 50% of mice develop liver adenomas with no sex difference detected

• neoplastic nodules are first detected after 11 months of age

neoplasm

increased liver adenoma incidence ( J:180294 )

• about 50% of mice develop liver adenomas with no sex difference detected

• neoplastic nodules are first detected after 11 months of age