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Phenotypes Associated with This Genotype
Genotype
MGI:5317836
Allelic
Composition		 Rit1tm1Dand/Rit1tm1Dand
Genetic
Background		 involves: 129S6/SvEvTac * Black Swiss
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rit1tm1Dand mutation (0 available); any Rit1 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
increased cellular sensitivity to hydrogen peroxide ( J:183038 )
• in mouse embryonic fibroblasts
• however, embryonic fibroblasts exposed to etoposide or tunicamycin exhibit normal survival

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory