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Phenotypes Associated with This Genotype
Genotype
MGI:5319094
Allelic
Composition		 Capn1tm1Dgen/Capn1tm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Capn1tm1Dgen mutation (2 available); any Capn1 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal leukocyte adhesion ( J:183585 )
• angiotensin II fails to increase leukocyte adhesion in mesenteric microcirculation unlike in wild-type mice

homeostasis/metabolism
decreased physiological sensitivity to xenobiotic ( J:183585 )
• angiotensin II fails to increase leukocyte adhesion in mesenteric microcirculation unlike in wild-type mice

cellular
abnormal leukocyte adhesion ( J:183585 )
• angiotensin II fails to increase leukocyte adhesion in mesenteric microcirculation unlike in wild-type mice

hematopoietic system
abnormal leukocyte adhesion ( J:183585 )
• angiotensin II fails to increase leukocyte adhesion in mesenteric microcirculation unlike in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory