Phenotypes Associated with This Genotype

Genotype
MGI:5427089

• Allelic Composition: Gpm6a^tm1.1Tahi/Gpm6a^tm1.1Tahi
• Genetic Background: involves: C57BL/6NCrlj * CBA/JNCrlj

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:184737 )

N • mice appear grossly normal

N • all major axon tracts, including the lateral olfactory tract, are established

N • cultured olfactory bulb explant axons extend well and are only slightly reduced in number

abnormal axon extension ( J:184737 )

• outgrowth inhibition by 1B4 antibody is completely abolished in both cultured olfactory bulb explants and in dissociated hippocampal cultures

reproductive system

reproductive system phenotype ( J:184737 )

N • homozygotes are fertile

cellular

abnormal axon extension ( J:184737 )

• outgrowth inhibition by 1B4 antibody is completely abolished in both cultured olfactory bulb explants and in dissociated hippocampal cultures