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Phenotypes Associated with This Genotype
Genotype
MGI:5427735
Allelic
Composition		 Rgs11tm1Lex/Rgs11tm1Lex
Rgs7tm1.1Kama/Rgs7tm1.1Kama
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6 * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rgs11tm1Lex mutation (2 available); any Rgs11 mutation (31 available)
Rgs7tm1.1Kama mutation (0 available); any Rgs7 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal rod electrophysiology ( J:184794 )
• mice lack dark-adapted electroretinogram b-wave

nervous system
abnormal single cell response ( J:184794 )
• rod ON bipolar cells lack a flash response and exhibit a 40-folder shorter light-evoked response compared with wild-type cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory