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Phenotypes Associated with This Genotype
Genotype
MGI:5427847
Allelic
Composition		 Gata3tm1Jfz/Gata3tm1Jfz
Zfp157Gt(XC356)Byg/Zfp157Gt(XC356)Byg
Tg(LGB-cre)74Acl/0
Genetic
Background		 involves: 129 * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata3tm1Jfz mutation (0 available); any Gata3 mutation (32 available)
Tg(LGB-cre)74Acl mutation (2 available)
Zfp157Gt(XC356)Byg mutation (0 available); any Zfp157 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:184505 )
N
• rescue of the lactation failure seen in mutant mice wild-type for Zfp157

integument
abnormal mammary gland luminal epithelium morphology ( J:184505 )
• mild epithelial dysplasia in all ducts and alveoli with an increase in the number of binucleate cells and cells of variable sizes

endocrine/exocrine glands
abnormal mammary gland luminal epithelium morphology ( J:184505 )
• mild epithelial dysplasia in all ducts and alveoli with an increase in the number of binucleate cells and cells of variable sizes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory