Phenotypes Associated with This Genotype

Genotype
MGI:5430802

• Allelic Composition: P2rx5^tm1Lex/P2rx5^tm1Lex
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

increased NK cell number ( J:82809 )

decreased CD8-positive, alpha-beta T cell number ( J:82809 )

• decreased peripheral blood CD8+ lymphocytes

immune system

increased NK cell number ( J:82809 )

decreased CD8-positive, alpha-beta T cell number ( J:82809 )

• decreased peripheral blood CD8+ lymphocytes

behavior/neurological

impaired cued conditioning behavior ( J:82809 )

• impaired learning/memory during trace aversive conditioning

increased exploration in new environment ( J:82809 )

• increased exploratory behavior during open field testing