Phenotypes Associated with This Genotype

Genotype
MGI:5431084

• Allelic Composition: Fig4^plt1/Fig4^plt1; Tg(Eno2-Fig4)#Mm/?
• Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6 * CAST/Ei * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:185989 )

• 65% of mice live 10 months or more

growth/size/body

abnormal postnatal growth ( J:185989 )

• growth rate is improved during the first month relative to Fig4^plt1 homozygotes

nervous system

nervous system phenotype ( J:185989 )

N • spongiform degeneration corrected at 3 weeks of age and in mice 9 and 12 months old

N • dorsal root ganglion spongiform degeneration also improved

N • sciatic nerve conduction velocity normal

N • normal sciatic nerve myelination