Phenotypes for Drd4 MGI:5431887 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Drd4^tm1Dkg/Drd4^tm1Dkg
Genetic Background	involves: 129P2/OlaHsd

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Drd4^tm1Dkg mutation (1 available); any Drd4 mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal eye electrophysiology ( J:185955 )

• overall light-adapted electroretinographic response is significantly reduced

• on day 2 in constant darkness, circadian regulation of the light-adapted electroretinographic response is abolished

abnormal vision ( J:185955 )

• optokinetic tracking indicates a decrease in contrast sensitivity over multiple spatial frequencies

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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