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Phenotypes Associated with This Genotype
Genotype
MGI:5432920
Allelic
Composition		 B2mtm1Unc/B2mtm1Unc
Tespa1tm1Smoc/Tespa1tm1Smoc
Genetic
Background		 involves: 129 * 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
B2mtm1Unc mutation (37 available); any B2m mutation (121 available)
Tespa1tm1Smoc mutation (1 available); any Tespa1 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal CD8-positive, alpha beta T cell morphology ( J:186446 )
• unlike in B2mtm1Unc homozygotes, CD8+ single positive thymocytes are detected in the thymus and spleen

hematopoietic system
abnormal CD8-positive, alpha beta T cell morphology ( J:186446 )
• unlike in B2mtm1Unc homozygotes, CD8+ single positive thymocytes are detected in the thymus and spleen

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory