Phenotypes Associated with This Genotype

Genotype
MGI:5433633

• Allelic Composition: Lamc2^jeb/Lamc2^jeb
• Genetic Background: B6.129X1-Lamc2^jeb/Dcr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

abnormal epidermal-dermal junction morphology ( J:186910 )

dermal-epidermal separation ( J:186910 )

• separation of the dermis from epidermis of the tail requires much less tensile strength for homozygotes at the earliest timepoint assessed, 4 weeks of age, and the requisite tensile strength decreases between 6 and 11 weeks in males and between 15 and 19 weeks in females

decreased skin tensile strength ( J:186910 )