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Phenotypes Associated with This Genotype
Genotype
MGI:5444176
Allelic
Composition
Pi4katm2.1Arte/Pi4ka+
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic
Background
involves: C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm9(cre/ESR1)Arte mutation (2 available); any Gt(ROSA)26Sor mutation (1024 available)
Pi4katm2.1Arte mutation (0 available); any Pi4ka mutation (126 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• 12 days following tamoxifen-treatment in male mice
• however, female mice remain normal

digestive/alimentary system
• following tamoxifen-treatment, male mice exhibit similar observations as in homozygous conditional knock-ins but with lower severity

behavior/neurological
• following tamoxifen-treatment in male mice
• however, female mice remain normal

growth/size/body
• following tamoxifen-treatment in male mice
• however, female mice remain normal

hematopoietic system
• following tamoxifen-treatment, one female mouse exhibited a black focal mild discoloration of the spleen

integument
• poor coat condition following tamoxifen-treatment in male mice
• however, female mice remain normal

immune system
• following tamoxifen-treatment, one female mouse exhibited a black focal mild discoloration of the spleen


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory

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