mortality/aging
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• 12 days following tamoxifen-treatment in male mice
• however, female mice remain normal
|
digestive/alimentary system
|
• following tamoxifen-treatment, male mice exhibit similar observations as in homozygous conditional knock-ins but with lower severity
|
behavior/neurological
|
• following tamoxifen-treatment in male mice
• however, female mice remain normal
|
growth/size/body
|
• following tamoxifen-treatment in male mice
• however, female mice remain normal
|
hematopoietic system
|
• following tamoxifen-treatment, one female mouse exhibited a black focal mild discoloration of the spleen
|
integument
|
• poor coat condition following tamoxifen-treatment in male mice
• however, female mice remain normal
|
immune system
|
• following tamoxifen-treatment, one female mouse exhibited a black focal mild discoloration of the spleen
|