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Phenotypes Associated with This Genotype
Genotype
MGI:5444495
Allelic
Composition		 Irx3tm3Hui/Irx3tm3Hui
Irx5tm3Hui/Irx5tm3Hui
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
Genetic
Background		 involves: FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A1cfTg(Myh6-cre/Esr1*)1Jmk mutation (5 available); any A1cf mutation (39 available)
Irx3tm3Hui mutation (0 available); any Irx3 mutation (25 available)
Irx5tm3Hui mutation (0 available); any Irx5 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
prolonged PR interval ( J:189007 )
• in tamoxifen treated mice
prolonged QRS complex duration ( J:189007 )
• in tamoxifen treated mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory