About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5446050
Allelic
Composition		 Tpcn1tm1.1Dren/Tpcn1tm1.1Dren
Tpcn2tm1.1Dren/Tpcn2tm1.1Dren
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tpcn1tm1.1Dren mutation (0 available); any Tpcn1 mutation (70 available)
Tpcn2tm1.1Dren mutation (0 available); any Tpcn2 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal macrophage physiology ( J:189070 )
• absence of PI(3,5)P2-activated TPC-like currents in isolated vacuoles

hematopoietic system
abnormal macrophage physiology ( J:189070 )
• absence of PI(3,5)P2-activated TPC-like currents in isolated vacuoles

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory