Phenotypes for Map3k7 Tg(Tek-cre)12Flv Tnfrsf1a MGI:5464102 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Map3k7^tm1Aki/Map3k7^tm1Aki Tnfrsf1a^tm1Mak/Tnfrsf1a^tm1Mak Tg(Tek-cre)12Flv/0
Genetic Background	involves: 129P2/OlaHsd * 129S2/SvPas * C3H * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k7^tm1Aki mutation (0 available); any Map3k7 mutation (54 available)
Tg(Tek-cre)12Flv mutation (1 available)
Tnfrsf1a^tm1Mak mutation (2 available); any Tnfrsf1a mutation (53 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:191285 )

• mice die by E13.5

cardiovascular system

cardiovascular system phenotype ( J:191285 )

N	• blood vessels do not exhibit regression and exhibit normal vessel length and branching

dilated vasculature ( J:191285 )

cellular

cellular phenotype ( J:191285 )

N	• embryonic endothelial cell apoptosis is rescued

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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