Phenotypes Associated with This Genotype

Genotype
MGI:5475105

• Allelic Composition: Gbp2^tm1.1Kpf/Gbp2^tm1.1Kpf
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:192526 )

N • morbidity and mortality due to Listeria monocytogenes is not substantially different from controls

increased susceptibility to parasitic infection ( J:192526 )

• cyst count is double that found in controls at 30 days after infection

• parasite replication is substantially increased

increased susceptibility to parasitic infection induced morbidity/mortality ( J:192526 )

• chronic Toxoplasma gondii infection results in steadily increasing mortality from 12 days through 60 days after infection whereas mortality of control mice does not increase until after 45 days

mortality/aging

increased susceptibility to parasitic infection induced morbidity/mortality ( J:192526 )

• chronic Toxoplasma gondii infection results in steadily increasing mortality from 12 days through 60 days after infection whereas mortality of control mice does not increase until after 45 days