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Phenotypes Associated with This Genotype
Genotype
MGI:5475534
Allelic
Composition		 Rdh10tm1c(KOMP)Wtsi/Rdh10tm1c(KOMP)Wtsi
Tg(Amh-cre)8815Reb/0
Genetic
Background		 involves: C57BL/6 * C57BL/6N * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rdh10tm1c(KOMP)Wtsi mutation (0 available); any Rdh10 mutation (20 available)
Tg(Amh-cre)8815Reb mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
seminiferous tubule degeneration ( J:193281 )
• about 45% of the tubules are degenerated at 2 and 3 weeks of age
decreased testis weight ( J:193281 )
• at 2 and 3 weeks of age
abnormal male reproductive system physiology ( J:193281 )
• numerous degenerated germ cells are present in the testes

endocrine/exocrine glands
seminiferous tubule degeneration ( J:193281 )
• about 45% of the tubules are degenerated at 2 and 3 weeks of age
decreased testis weight ( J:193281 )
• at 2 and 3 weeks of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory