Phenotypes Associated with This Genotype

Genotype
MGI:5484563

• Allelic Composition: Smn1^tm1Hung/Smn1^tm1Hung; Tg(SMN2)2Hung/0
• Genetic Background: FVB.Cg-Smn1^tm1Hung Tg(SMN2)2Hung/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:193844 )

• Background Sensitivity: mice on an FVB/N background exhibit decreased survival compared with mice on a C57BL/6N or mixed background

nervous system

abnormal neuromuscular synapse morphology ( J:193844 )

• Background Sensitivity: mice on an FVB/N background exhibit smaller endplate size compared with mice on a mixed background

muscle

decreased skeletal muscle fiber size ( J:193844 )

• Background Sensitivity: mice on an FVB/N background exhibit smaller muscle fiber size compared with mice on a mixed background