Phenotypes Associated with This Genotype

Genotype
MGI:5490260

• Allelic Composition: enu164/enu164⁺; Tg(Thy1-MAPT*K369I)K3Gotz/0
• Genetic Background: involves: BALB/c * C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:196547 )

• at 6 weeks, some mice exhibit improved motor impairments (reduced severity of abnormal gait, clasping and tremor) compared with Tg(Thy1-MAPT*K369I)K3Gotz mice

limb grasping ( J:196547 )

• improved at 6 weeks compared with Tg(Thy1-MAPT*K369I)K3Gotz mice

tremors ( J:196547 )

• improved at 6 weeks compared with Tg(Thy1-MAPT*K369I)K3Gotz mice

abnormal gait ( J:196547 )

• improved at 6 weeks compared with Tg(Thy1-MAPT*K369I)K3Gotz mice